How to Use Genetic Genie with Your 23andMe DNA Results

If you are reading this and wonder what a 23andMe DNA test is, check out my last post.

Otherwise, if you’ve received your 23andMe results and want to figure out whether you have any MTHFR or other methylation cycle mutations, you might want to use GeneticGenie.org to make this process simpler.  GeneticGenie.org is a site that allows you to upload your raw 23andMe data for analysis.  It spits out a nice, easy to understand report regarding your methylation cycle SNPs included in the 23andMe result set. 

Privacy Concerns?

Genetic Genie does not store your data. And, even if they did, I think you have much more to gain by getting the results than you have to lose if some researcher happened to keep your results. However, they do not store your data.  Nevertheless, if you rename the zip file and its contents that you download from 23andMe, the Genetic Genie site will not have your name. The content of the zip file contains only raw data for the genes. The data does not contain your name or other personal information. You can open the text file and see that this is true. Otherwise, the HTTP request you send to their server is no different from any other request anywhere else on the internet like browsing to this post, so you have nothing to worry about. 

Step 1 – Get Your Raw Data

  1. To get your raw data for Genetic Genie, first log in to the 23andMe site.
  2. Click on the “Gears” icon on the upper left-hand corner and choose the “Browse Raw Data” menu option.
  3. Then, on the upper right, click, “download raw data.”

23andme

The data file you save to your computer will be called something like “genome_YourFirstName_YourLast­Name_….zip”.

Step 2 – Optionally Ensure Anonymity

Do this only if you are concerned about sending your name to Genetic Genie:

  1. Navigate to the downloaded zip file on your computer.
  2. Extract it.
  3. Rename the extracted .txt file to something innocuous like “raw_data.txt.” Your name is not inside the text file, so now the raw data is essentially anonymous.
  4. Now make a new zip from “raw_data.txt” which by default will be called “raw_data.zip.”

Step 3 – Genetic Genie

  1. Navigate to GeneticGenie.org.
  2. Click the “Methylation Analysis” tab.
  3. Follow the instructions to upload the file on the Methylation Analysis tab.  (You can also upload your data to the Detoxification Analysis tab.)

Bam!  When you get your lovely color-coded analysis, you’ll have a lot of fun learning about your SNPs and you will surely generate many new leads to follow as you sleuth out what you can do to to restore your health.

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One Response to How to Use Genetic Genie with Your 23andMe DNA Results

  1. Pingback: Good Lord, People, 23andMe is NOT Dead! | Emerging Technologies Librarian

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