How to Use Genetic Genie with Your 23andMe DNA Results

If you are reading this and wonder what a 23andMe DNA test is, check out my last post.

Otherwise, if you’ve received your 23andMe results and want to figure out whether you have any MTHFR or other methylation cycle mutations, you might want to use to make this process simpler. is a site that allows you to upload your raw 23andMe data for analysis.  It spits out a nice, easy to understand report regarding your methylation cycle SNPs included in the 23andMe result set. 

Privacy Concerns?

Genetic Genie does not store your data. And, even if they did, I think you have much more to gain by getting the results than you have to lose if some researcher happened to keep your results. However, they do not store your data.  Nevertheless, if you rename the zip file and its contents that you download from 23andMe, the Genetic Genie site will not have your name. The content of the zip file contains only raw data for the genes. The data does not contain your name or other personal information. You can open the text file and see that this is true. Otherwise, the HTTP request you send to their server is no different from any other request anywhere else on the internet like browsing to this post, so you have nothing to worry about. 

Step 1 – Get Your Raw Data

  1. To get your raw data for Genetic Genie, first log in to the 23andMe site.
  2. Click on your username in the upper right-hand corner and choose the “BROWSE RAW DATA” menu option.
  3. Then, on the upper right, click, “DOWNLOAD.”


  1. Complete the form, selecting, “All Data” for your Data Set.
  2. Finally, click “Download Data.”

The data file you save to your computer will be called something like “genome_YourFirstName_YourLast­Name_….zip”.

Step 2 – Optionally Ensure Anonymity

Do this only if you are concerned about sending your name to Genetic Genie:

  1. Navigate to the downloaded zip file on your computer.
  2. Extract it.
  3. Rename the extracted .txt file to something innocuous like “raw_data.txt.” Your name is not inside the text file, so now the raw data is essentially anonymous.
  4. Now make a new zip from “raw_data.txt” which by default will be called “”

Step 3 – Genetic Genie

  1. Navigate to
  2. Click the “Methylation Analysis” tab.
  3. Follow the instructions to upload the file on the Methylation Analysis tab.  (You can also upload your data to the Detoxification Analysis tab.)

Bam!  When you get your lovely color-coded analysis, you’ll have a lot of fun learning about your SNPs and you will surely generate many new leads to follow as you sleuth out what you can do to to restore your health.

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12 Responses to How to Use Genetic Genie with Your 23andMe DNA Results

  1. Pingback: Good Lord, People, 23andMe is NOT Dead! | Emerging Technologies Librarian

  2. Melissa says:

    Thanks so much for this service! You might want to update the instructions since the icons/navigator instructions on 123youandme. I’m going to share this info on fb!

  3. Livewello says:

    Thought we’d piggy back with our directions for those who’d need it too and run into this blog.
    Directions to get your raw data from 23andMe and then upload your Raw Data to Livewello:

    1. Download your 23andMe raw data and save it to your computer’s desktop by going here:

    2. Go to and upload your file from your desktop.

    3. What to do after you receive your Gene Results:

    You can manage multiple people with 1 account/email. To add new profiles:
    – Click on the profile selector ( On the top navigation bar, where your name and photo is)
    – Select “Add new profile”

    -To start using the Ap, first generate their standard gene report: select the “Genetics” tab, then “Variance reports”

    Did you Know?
    You can compare reports and any templates you install using the Compare Reports Tool. It allows you to view and compare up to 5 different people’s variance reports side-by-side.

    Comparing your Gene Reports side-by-side with friends or family profiles in your Account: Video:

    How does an App help with your Genetic Raw Data Results?

    Search and install as many Health Reports as you like here:

    What does the Gene App do?

    Thanks for all you do Bekah!

    Customer Support

  4. This was not helpful 😦 once I entered my information, all it did was send me to results that bluntly says “This information is intended for those who have some understanding in single nucleotide polymorphisms” I can’t fecking read what that list means 😦 haha wtf. Is there a site that says what that means? Please somebody help with some real advice!!!

  5. bfree2day says:

    I believe honorstransferclub is referring to the Detox Profile Tab on Genetic Genie. When you download your data, that’s what it says at the very beginning. But if you click on the “Methylation Analysis” tab and follow instructions from there, I think you’ll find what you’re looking for.
    Instructions on this post were very helpful by the way ~ Thanks!

  6. Kathy K. says:

    Does one need to order the $199 Health and Ancestry 23andme kit or will the $99 ancestry kit provide raw data for Genetic Genie? Apologies if this has already been covered! THank you!

  7. Frances Womack says:

    I only have a list of rsID,s in a file from 23 and me. This is in txt form and i need it in a form that I can understand… ex. gene mutations. Can you work with this?

    • rchill says:

      Hey! It sounds like you may have the “Raw Data File,” the txt file, from 23andMe. If that is the case, you could try “Step 3” from this post to upload the raw data to There may be some small variations from the instructions given on this blog post because their website may have changed since I originally made this post. Nevertheless, I was just able to access the Methylation Analysis and Detox Profile on report today with my Raw Data File. For advanced research, you could try searching individual mutations at

  8. Adriana says:

    I recently got my MTHFR status report from Xcode Life and I was very impressed by the results.

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